Stability of Pro-Gastrin-Releasing Peptide in Serum versus Plasma
نویسندگان
چکیده
منابع مشابه
Stability of pro-gastrin-releasing peptide in serum versus plasma.
BACKGROUND/AIMS Although serum assays for pro-gastrin-releasing peptide (ProGRP) assays have been commercially available in Japan for several years, the stability of ProGRP in serum and plasma has not been well documented. We investigated the stability of ProGRP in serum and plasma with fresh and stored (frozen) specimens, as well as the cause of the observed instability in serum. METHODS/RES...
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The aim of our study was to evaluate the usefulness of serum OPG and ProGRP during chemotherapy of lung cancer in relation to the histological type of the tumour, its clinical stage and the response to therapy. The levels of OPG and ProGRP were determined in 39 patients (20 NSCLC, 19 SCLC) and 10 healthy subjects. Blood samples were collected from each patient before and after chemotherapy. OPG...
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Accepted for publication 9 November 1995 Abstract Background-Patients with duodenal ulcer (DU) have high basal (BAO) and peak (PAO) acid outputs. The effect of Helicobacter pylori eradication on these variables is unclear. Aim-To discover if gastric acid hypersecretion in patients with DU is caused by Hpylori. Patients and methods-BAO, gastrin releasing peptide (GRP), and pentagastrin stimulate...
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AIMS To establish whether gastrin releasing peptide (GRP) and the GRP receptor (GRPR) are expressed together in gastrointestinal carcinoid tumours. METHODS Twenty six carcinoid tumours from the stomach, small intestine, appendix, and colorectum were investigated by immunohistochemistry for GRP and GRPR. RESULTS GRP was detected in nine of 19 tumours and GRPR in 22 of 26. Coexpression of bot...
متن کاملMolecular basis of the selectivity of gastrin-releasing peptide receptor for gastrin-releasing peptide.
The mammalian bombesin peptides [gastrin-releasing peptide (GRP) and neuromedin B (NMB)] are important in numerous biological and pathological processes. These effects are mediated by the heptahelical GRP receptor (GRPR) and NMB receptor (NMBR). GRP has high affinity for GRPR and lower affinity for NMBR. Almost nothing is known about the molecular basis for the selectivity of GRP. To address th...
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ژورنال
عنوان ژورنال: Tumor Biology
سال: 2008
ISSN: 1423-0380,1010-4283
DOI: 10.1159/000152940